Search
Now showing items 1-16 of 16
Canine Neurodegenerative Diseases: A Bridge from Bench to Health for Humans and their Companions
(2010)
Spontaneous neurologic diseases are common in dogs and frequently there is a genetic predisposition. Advances in canine genomics and the nature of pure-bred dog populations make it possible to efficiently map and sequence ...
Navigating the two-way street of comparative oncology
(2010)
Companion animals offer a unique model for study of spontaneously occurring cancer for many reasons. Our pets share our environment, thus may have similar exposure to environmental carcinogens. The technology for diagnosis ...
Shelter Dog Behavior Improvement: Dog Walking as Enrichment
(2010)
Background: Several million dogs are euthanized in animal shelters annually after multiple relinquishment reasons (Scarlett, 2002; Salman, 1998; New, 2000 & Kass, 2001). Gains in pet adoptions are happening via shelter ...
Comparative oncology and clinical translation of glyco protein conjugated gold nano therapeutic agent (GA-198AuNP) [abstract]
(2010)
As part of our efforts toward clinical translation of GA-198AuNP, our studies are focused on therapeutic efficacy of nanoparticulate GA198AuNP agent in dogs with prostatic carcinoma. The overall goal is to gain clinical ...
Walk A Hound, Lose A Pound, & Stay Fit for Seniors
(2010)
Background: Obesity rates in older adults are linked with the national problem of limited physical activity (PA), resulting in chronic illness. Obesity-related illness and functional loss require innovative interventions. ...
Comparative imaging of canine shoulder osteochondrosis lesions
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Over the last several years, papers have been published describing imaging techniques for the canine shoulder joint using both ultrasound and magnetic ...
Dose escalation safety study of Nanotax® in dogs [abstract]
(2010)
The goal of this project is to determine the suitability of CritiTech's existing formulation of fine-particle paclitaxel, Nanotax®, for the treatment of spontaneously-occurring cancer in dogs. The rationale behind this ...
Comprehensive characterization of canine meniscal pathology
(University of Missouri--Columbia, 2010)
Meniscal injury is one of the most common causes of pain and dysfunction in the human knee and canine stifle joint. In the canine patient, meniscal injury is usually secondary to cranial cruciate ligament rupture, and the ...
The antiendotoxin effects of polymyxin B in a feline model of endotoxemia
(University of Missouri--Columbia, 2010)
Introduction: Directed, effective therapies for feline sepsis are needed to reduce the high morbidity and mortality associated with this disease. Materials and Methods: We investigated the anti-endotoxin effects of PMB in ...
Canine T-regulatory cells in aging and cancer : quantifying a unique T cell subset
(University of Missouri--Columbia, 2010)
T regulatory lymphocytes (Tregs), identified by the markers CD4, CD25, and FoxP3, are an essential part of the immune system and promote tolerance with the purpose of minimizing auto-immune disease. However, if Tregs are ...
Longitudinal evaluation of effects of adipose-derived mesenchymal stem cells in a model of feline allergic asthma
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Asthma is characterized by airway inflammation, airway hyperresponsiveness (AHR), and structural changes in the lungs. Mesenchymal stem cells (MSCs) ...
Development of an in-vitro model of equine corneal wound healing : pharmacologic and gene therapy modalities in the reduction of corneal fibrosis
(University of Missouri--Columbia, 2010)
Objective: To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was ...
Acute phase proteins in naturally occurring respiratory disease of feedlot cattle : a novel approach to diagnosisAcute phase proteins in naturally occurring respiratory disease of feedlot cattle : a novel approach to diagnosis
(University of Missouri--Columbia, 2014)
Bovine respiratory disease (BRD) is the most costly disease of feedlot cattle in the United States. Costs associated with BRD have been estimated from $13.90 to $15.57 per head with annual losses to the cattle industry ...
Evaluation of autoimmune disease as a risk factor for lymphoma
(University of Missouri--Columbia, 2013)
The immune system has an intricate relationship with cancer. It is responsible for the prevention, management, and resolution of cancer. In people and dogs autoimmune diseases have been linked to hematopoietic neoplasia. ...
Clinical and Computational Collaboration in Orthopaedic Biomechanics
(2010)
The mission of the Comparative Orthopaedic Laboratory at the University of Missouri-Columbia (COL-UMC) is three-fold: 1.To design and conduct the highest quality hypothesis-driven research focused on orthopaedic disorders ...
Transcriptome profiling of rattus norvegicus embryonic stem cells by RNA-sequencing
(University of Missouri--Columbia, 2014)
Embryonic Stem Cells (ESCs) are a critical tool for producing targeted knockout animals and understanding development. ESCs were successfully isolated from rats in 2008 and have been used in producing several targeted ...