RSS 1.0Veterinary Medicine and Surgery electronic theses and dissertations (MU)
The items in this collection are the theses and dissertations written by students of the Department of Veterinary Medicine and Surgery. Some items may be viewed only by members of the University of Missouri System and/or University of Missouri-Columbia. Click on one of the browse buttons above for a complete listing of the works.
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Recent Submissions
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Locoregional techniques for dogs undergoing tibial plateau leveling osteotomy : a literature review, anesthesiologist survey, and future directions
(University of Missouri--Columbia, 2023)Over the past several decades there have been significant advancements in our understanding and ability to provide effective analgesia to animals undergoing elective orthopedic surgery through methods that can help us ... -
Prolonged survival in 58 dogs with thyroid carcinoma treated with radioactive iodine as sole therapy
(University of Missouri--Columbia, 2023)Treatment of thyroid carcinomas in people and dogs often involves multimodal therapy, including radioactive iodine (I-131). The objective of this study is to describe outcomes associated with I-131 as sole therapy in dogs ... -
Neonatal beef calf morbidity and mortality in Missouri
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 12/1/2023] Neonatal morbidity and mortality are major causes of economic loss for US beef cattle producers. The Missouri cattle industry represents 19 percent of the total agriculture sales in the state ... -
Diagnosis of aerodigestive disorders in dogs utilizing videofluoroscopic swallow study
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 12/1/2023] An aerodigestive disease (AeroD) is a disorder pathologically linking the respiratory and alimentary tracts. Dogs having respiratory signs without dysphagia, vomiting, or regurgitation typically ... -
Relative HER2 protein expression in normal canine tissue and canine osteosarcoma
(University of Missouri--Columbia, 2022)Development of HER2-targeted immunotherapy in canine osteosarcoma (OSA) is underway, yet HER2 expression in normal and neoplastic canine tissue has not yet been defined. This study's objective was to evaluate the relative ... -
A quantitative evaluation of DNA damage from irradiation of feline oral squamous cell carcinoma cells
(University of Missouri--Columbia, 2022)Feline oral squamous cell carcinoma is a locally invasive neoplasm that continues to carry a poor prognosis despite advances in multimodality oncologic treatment. Location, completeness of surgical excision or complete ... -
Biochemical characteristics of different subtypes of human immunodeficiency virus type 1 reverse transcriptase and its interactions with the host factor : apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Human immunodeficiency virus (HIV) is divided into type 1 (HIV-1) and type 2 (HIV-2). Whereas HIV-2 accounts for 5% of global infections, HIV-1 is ... -
Transcriptome profiling of rattus norvegicus embryonic stem cells by RNA-sequencing
(University of Missouri--Columbia, 2014)Embryonic Stem Cells (ESCs) are a critical tool for producing targeted knockout animals and understanding development. ESCs were successfully isolated from rats in 2008 and have been used in producing several targeted ... -
Analysis of platlet function in the setting of controlled trauma in dogs using a whole blood electrical impedance platelet aggregometer
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Post-traumatic hemorrhage remains one of the leading causes of human deaths, accounting for 30 to 56 percent of pre-hospital post-traumatic deaths. ... -
In vitro and ex vivo therapeutic strategies for equine corneal fibrosis
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Purpose: The aims were to (1) To explore the impact of equine corneal fibroblast (ECF) to myofibroblast (ECM) differentiation by altering the expression ... -
The use of sodium iodide for the management of bovine respiratory disease
(University of Missouri--Columbia, 2017)Objective: The purpose of these studies was to (1) determine the effect of a single dose of oral sodium iodide on weaned beef calves and (2) determine the outcome of clinical application of a single dose of oral sodium ... -
Assessment of behavioral, neurochemical and developmental effects in developing rats following in utero exposure to non-teratogenic levels of 2,4-D and 2,4,5-T
(University of Missouri--Columbia, 1984)The safe or non-teratogenic levels following prenatal exposure of animals to chlorophenoxy herbicides are currently based on offspring survival, growth and absence of anatomical defects or overt neurological impairment. ... -
Interaction of organophosphorus insecticide (Ciovap(R)) with phenothiazine anthelmintic in sheep with or without Haemonchus and Trichostrongylus species infection
(University of Missouri -- Columbia., 1981)"This study was undertaken to examine the extent of cholinesterase inhibition and clinical effects of repeated topical application of the organophosphorus insecticide (Ciovap (R)) and the oral administration of phenothiazine ... -
The use of ventilator-acquired pulmonary mechanics and computed tomography in the assessment of interventions for experimental feline asthma
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In an experimental model of feline asthma, computed tomography (CT) and ventilator-acquired pulmonary mechanics were used in the assessment of various ... -
Therapeutic potential of the anti-fibrotic drug Suberanilohydroxamic acid (SAHA) in canine corneal fibrosis
(University of Missouri--Columbia, 2016)Purpose: The aims were to (1) investigate the molecular mechanisms mediating the antifibrotic effect of SAHA in the canine cornea using an in vitro model and (2) to develop a novel in vivo model of corneal fibrosis in dogs ... -
Angular limb deformities affecting the canine radius and ulna : classification using the center of rotation of angulation method
(University of Missouri--Columbia, 2015)We hypothesized that 1) antebrachial ALDs would be more complex with respect to multiplicity in chondrodystrophic dogs, and 2) more complex ALDs would exhibit a higher incidence of concurrent joint radiographic disease. ... -
Longitudinal evaluation of effects of adipose-derived mesenchymal stem cells in a model of feline allergic asthma
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Asthma is characterized by airway inflammation, airway hyperresponsiveness (AHR), and structural changes in the lungs. Mesenchymal stem cells (MSCs) ... -
Development of an in-vitro model of equine corneal wound healing : pharmacologic and gene therapy modalities in the reduction of corneal fibrosis
(University of Missouri--Columbia, 2010)Objective: To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was ... -
Acute phase proteins in naturally occurring respiratory disease of feedlot cattle : a novel approach to diagnosis
(University of Missouri--Columbia, 2014)Bovine respiratory disease (BRD) is the most costly disease of feedlot cattle in the United States. Costs associated with BRD have been estimated from $13.90 to $15.57 per head with annual losses to the cattle industry ... -
Evaluation of autoimmune disease as a risk factor for lymphoma
(University of Missouri--Columbia, 2013)The immune system has an intricate relationship with cancer. It is responsible for the prevention, management, and resolution of cancer. In people and dogs autoimmune diseases have been linked to hematopoietic neoplasia. ...