Can human xylosyltransferase-1 serve as a biomarker and therapeutic target for corneal fibrosis?
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Tested was the hypothesis that XYLT1 plays an important role in corneal wound healing and scarring and may allow development of newer strategies for curing corneal fibrosis. The specific aims were: 1) to characterize XYLT1 expression in normal and wounded human and rabbit corneas, 2) investigate its role in corneal wound healing, and 2) determine whether XYLT1 can serve as a biomarker for corneal fibrosis.
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