Browsing 2016 MU theses - Freely available online by Thesis Advisor "Cheng, Jianlin"
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EM algorithm for reconstructing 3D structures of human chromosomes from chromosomal contact data
(University of Missouri--Columbia, 2016)Recent research suggested that chromosomes have preferred spatial conformations to facilitate necessary long-range interactions and regulations within a nucleus. So that, getting the 3D shape of chromosomes of a genome is ... -
Gene expression prediction based on deep learning
(University of Missouri--Columbia, 2016)Gene expression is a critical process in a biological system that is influenced and modulated by many factors including genetic variation. Thus, it is important to understand how genotypes affect the gene expression levels. ...