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dc.contributor.advisorGrant, Sheila Anneng
dc.contributor.authorVassalli, J. Toddeng
dc.date.issued2008eng
dc.date.submitted2008 Falleng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on October 6, 2009).eng
dc.descriptionThesis advisor: Dr. Sheila Grant,eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionM.S. University of Missouri--Columbia 2008.eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Biological engineering.eng
dc.description.abstractIn order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. The first step in creating this bionanocomposite material is to develop a method to produce and functionalize bioabsorbable polymer fibers. Electrospinning was chosen for its effectiveness and cost efficiency in producing polymer fibers in the sub-micron range. For this project, an electrospinning solution consisting of the degradable polymer polycaprolactone is treated with the aminolyzing agent ethylenediamine in order to add amine groups to the resulting electrospun fibers. Amine-group functionalization is measured using FT-IR scans of electrospun test samples. The degree of sample functionalization is measured as a numeric area of the respective amine peaks from the resulting FT-IR absorbance graphs. Current research findings indicate that it is possible to produce functionalized polycaprolactone fibers in the sub-micron range based on this experimental method.eng
dc.identifier.merlinb71551426eng
dc.identifier.oclc449946599eng
dc.identifier.urihttps://hdl.handle.net/10355/5631
dc.identifier.urihttps://doi.org/10.32469/10355/5631eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.source.originalSubmitted by University of Missouri--Columbia Graduate School.eng
dc.subject.lcshHernia -- Surgeryeng
dc.subject.lcshElectrospinningeng
dc.subject.lcshBiomedical materialseng
dc.titleDevelopment of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair materialeng
dc.typeThesiseng
thesis.degree.disciplineBiological engineering (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelMasterseng
thesis.degree.nameM.S.eng


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