How do clinical prediction rules compare with joint fluid analysis in diagnosing gout?
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Q: How do clinical prediction rules compare with joint fluid analysis in diagnosing gout? Evidence-based answer: Clinical prediction rules effectively diagnose gout without joint fluid analysis. The American College of Rheumatology clinical prediction rules, the most accurate rules developed for research purposes, have a sensitivity of 92%, specificity of 89%, positive likelhood rati of 8.36, and negative likelihood ratio of 0.09 (strength of recommendation [SOR]: A, prospective cohort studies). The Netherlands criteria, developed for use in primary care, have a positive predictive value of more than 80%, a positive likelihood ratio of 3.48, and a negative likelihood ratio of 0.17 (SOR: A, prospective cohort study).
Journal of Family Practice, 65(11) 2016: 835-837.