Functional outcome and self-perceived overall health status following surgery to remove primary brain tumor

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Functional outcome and self-perceived overall health status following surgery to remove primary brain tumor

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/5754

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dc.contributor.advisor Litofsky, N. Scott (Norman Scott), 1959- en_US
dc.contributor.advisor Chandrasekhar, Anand, 1965- en_US
dc.contributor.author Krug, Jeffrey Bart en_US
dc.date.accessioned 2010-02-23T17:15:32Z
dc.date.available 2010-02-23T17:15:32Z
dc.date.issued 2008 en_US
dc.date.submitted 2008 Fall en
dc.identifier.other KrugJ-121008-T11711 en_US
dc.identifier.uri http://hdl.handle.net/10355/5754
dc.description The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. en_US
dc.description Title from PDF of title page (University of Missouri--Columbia, viewed on September 25, 2009). en_US
dc.description Thesis advisors: Dr. N. Scott Litofsky & Dr. Anand Chandrasekhar. en_US
dc.description Includes bibliographical references. en_US
dc.description M.S. University of Missouri--Columbia 2008. en_US
dc.description Dissertations, Academic -- University of Missouri--Columbia -- Neuroscience. en_US
dc.description.abstract Impaired functional abilities, especially those associated with ambulation and standing balance, are common sequelae of brain tumors. A majority of research regarding the effectiveness of surgery in treating individuals with brain tumor (BT) has measured length of survival, recurrence rate, and amount of tumor removed. Objective measurements of functional abilities and self-perceived overall health status (OHS) prior to and after surgery are important aspects of treatment, yet these areas have been inadequately studied. 9 adults with diagnosis of primary brain tumor were assessed prior to, immediately following, and at 3 months after surgery using the Timed Up-and-Go (TUG) and Tinetti Performance-Oriented Mobility Assessment (Tinetti) and Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Repeated measures ANOVA demonstrated significant differences in all outcome measures from pre- to immediately post-surgery with OHS (SF-36: df=1, F=6.3, p=0.04) and physical functioning (TUG: df=1, F=6.4, p=0.05; Tinetti: df=1, F=7.2, p=0.03) and from immediately post-surgery to 3 months post-surgery, ( SF-36: df=1, F=14.8, p=0.006; TUG: df=1, F=24.3, p=0.003; Tinetti: df=1, F=39.0, p<0.001). From pre-surgery to 3 months post-surgery, no significant difference was noted for any outcome measure (SF-36: df=1, F=2.3, p=0.18; TUG: df=1, F=0.03, p=0.86); Tinetti: df=1, F=3.4, p=0.11). All measures' post-surgery scores significantly correlated post-surgery. This included the two physical functioning measures (TUG and Tinetti) immediately post-surgery (r=-0.833, p=0.01) and 3 months post-surgery (r=-0.966, p=0.0). It also included the OHS and physical functioning measures: SF-36 and TUG (r=-0.762, p=0.028) and SF-36 and Tinetti immediately post-surgery (r=0.883, p=0.002); SF-36 and TUG (r=-0.845, p=0.004), and SF-36 and Tinetti 3 months post-surgery (r=0.849, p=0.004). Physical functioning and self-perceived OHS are closely linked. It is recommended that future studies of surgery for brain tumor use measures of physical functioning and OHS. The TUG, Tinetti, and SF-36 are appropriate for these purposes. en_US
dc.language.iso en_US en_US
dc.publisher University of Missouri--Columbia en_US
dc.relation.ispartof 2008 Freely available theses (MU) en_US
dc.subject.lcsh Brain -- Tumors -- Surgery en_US
dc.subject.lcsh Postoperative care en_US
dc.title Functional outcome and self-perceived overall health status following surgery to remove primary brain tumor en_US
dc.type Thesis en_US
thesis.degree.discipline Neuroscience en_US
thesis.degree.grantor University of Missouri--Columbia en_US
thesis.degree.name M.S. en_US
thesis.degree.level Masters en_US
dc.identifier.merlin .b71336953 en_US
dc.identifier.oclc 439880965 en_US
dc.relation.ispartofcommunity University of Missouri-Columbia. Graduate School. Theses and Dissertations. Theses. 2008 Theses


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