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dc.contributor.authorBattle, Deletria S.eng
dc.contributor.authorNorton, Lisa K.eng
dc.contributor.authorTucker, Sheryl A. (Sheryl Ann)eng
dc.contributor.corporatenameUniversity of Missouri-Columbia. Office of Undergraduate Researcheng
dc.contributor.meetingnameSummer Undergraduate Research and Creative Achievements Forum (2006 : University of Missouri--Columbia)eng
dc.date.issued2006eng
dc.descriptionAbstract only availableeng
dc.descriptionFaculty Mentor: Dr. Sheryl Tucker, Chemistryeng
dc.description.abstractPrevious spectroscopic investigations, utilizing the fluorescent reporter molecule phenol blue, showed that that the probe resided in the core region of dendritic polymers. Two dendrimer families were investigated - propyleneimine (PPI) and polyamido amine (PAMAM). This dye molecule provided information about the interior microenvironment of the dendrimers, which are potentially useful in applications ranging from sensors to catalysis to microreactors to drug carriers. Given their beneficial uses, the dendrimers ability to act as container molecules was further characterized in this study. Water was used as the original solvent because phenol blue is only slightly soluble in it, and the dye is attracted to the hydrophobic interior of the dendrimer. Phenol blue was added to aqueous solutions of PPI and PAMAM dendrimers of varying sizes and analyzed. Absorption, anisotropy, and fluorescence emission measurements were taken to show that phenol blue dye did associate with the dendrimer in the core region as expected. Samples were then heated to remove the water, and the solvent was replaced by adding methanol to the samples. Methanol was chosen because both phenol blue and the dendrimers are very soluble in it. This solvent should provide an opportunity for the dye to diffuse back into the bulk solution. The experimental measurements were repeated and revealed that phenol blue remains inside the dendrimers, once it is associated. This makes their utility as transporter molecules, etc. very desirable, as the payload can be retained.eng
dc.identifier.urihttp://hdl.handle.net/10355/587eng
dc.publisherUniversity of Missouri--Columbia. Office of Undergraduate Researcheng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. Office of Undergraduate Research. Undergraduate Research and Creative Achievements Forumeng
dc.source.urihttp://undergradresearch.missouri.edu/forums-conferences/abstracts/abstract-detail.php?abstractid=677eng
dc.subjectdendritic polymerseng
dc.subjectspectroscopic investigationseng
dc.subjectphenol blueeng
dc.titleSpectroscopic Investigations of Dendritic Polymers with Phenol Blue [abstract]eng
dc.typePresentationeng


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