Are beta-blockers effective for the treatment of infantile hemangiomas?
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Are beta-blockers effective for the treatment of infantile hemangiomas? EVIDENCE-BASED ANSWER: Treatment of infantile hemangiomas (IH) with oral propranolol (3 mg/kg per day) for 6 months results in complete or near complete resolution in 60% of babies compared with spontaneous resolution in 4% (SOR: B, large RCT). Propranolol results in at least some improvement in more than 97% of treated infants. Oral propranolol may be more effective than oral steroids and serious adverse events (AEs) are rare (SOR: B, systematic reviews of mostly observational studies).
Evidence-based practice 19, no. 12 (2016): 8-9