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    • University of Missouri-Columbia
    • Graduate School - MU Theses and Dissertations (MU)
    • Theses and Dissertations (MU)
    • Dissertations (MU)
    • 2007 Dissertations (MU)
    • 2007 MU dissertations - Access restricted to UM
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    Modeling and analysis of nonlinear biological systems

    Iyoho, Anthony E., 1978-
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    [PDF] research.pdf (1.099Mb)
    Date
    2007
    Format
    Thesis
    Metadata
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    Abstract
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This dissertation focuses on the modeling and analysis of a set of biological phenomenon at a cellular (Part I) and systems (Part II) level. In Part I, the development and analysis of a biologically realistic single neuronal model that alone can mimic resonance filtering properties seen in the in behavioral data in a species of katydid is outlined. Additionally, a network level model of the BLA-NAc pathway was developed to investigate how dopamine and glutamate modulate the cue-primed relapse circuitry. In Part II, a systematic approach to determine correction factors on individual characteristics was developed to adjust the tolerance time predictions of an 'average' computational model of heat strain. Additionally, a new computational model of the human thermal system was developed that accounts for asymmetric environments and includes the arteriovenous anastomoses (AVAs) to provide finer prediction of toe and fingertip temperatures.
    URI
    https://doi.org/10.32469/10355/6012
    https://hdl.handle.net/10355/6012
    Degree
    Ph. D.
    Thesis Department
    Mechanical and aerospace engineering (MU)
    Rights
    Access is limited to the campuses of the University of Missouri.
    Collections
    • 2007 MU dissertations - Access restricted to UM
    • Mechanical and Aerospace Engineering electronic theses and dissertations (MU)

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