Fluticasone plus salmeterol in persistent stable asthma likely safe
Bottom line: Clinicians have additional assurance of safety and efficacy when following current treatment guidelines to use long-acting beta-agonists in combination with inhaled glucocorticoids as recommended. It is unclear if this assurance can be applied to patients with unstable and severe asthma.Review and summary of: Stempel DA, Raphiou IH, Kral KM, et al. Serious asthma events with fluticasone plus salmeterol versus fluticasone alone. N Engl J Med. 2016; (19):1822-1830.
Evidence-based practice 20, no. 4 (2017): E12