Melatonin : it ain't just for sleep anymore
Bottom line: Melatonin is an option for migraine prophylaxis, as it appears as effective as amitriptyline for migraine prevention with fewer adverse effects.Review and summary of: Goncalves AL, Martini Ferreira A, Ribeiro RT, et al. Randomised clinical trial comparing melatonin 3 mg, amitriptyline 25 mg and placebo for migraine prevention. J Neurol Neurosurg Psychiatry. 2016; pii: jnnp-2016-313458.
Evidence-based practice 20, no. 4 (2017): 04