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    Do oral decongestants have a clinically significant effect on BP in patients with hypertension?

    Hollander- Rodriguez, Joyce C.
    Montjoy, Holly L.
    Smedra, Brynn
    Prouty, J. P.
    Hamilton, Andrew
    Guthmann, Richard
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    [PDF] JFP06606001e.pdf (71.48Kb)
    Date
    2017
    Format
    Article
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    Abstract
    Q: Do oral decongestants have a clinically significant effect on BP in patients with hypertension? Evidence-based answer: It is unclear. Pseudoephedrine causes an average increase of 1.2 mm Hg in systolic blood pressure (BP) in patients with controlled hypertension. However, the studies are not adequately powered to provide evidence about whether this rise in systolic BP is linked to patient-oriented outcomes (strength of recommendation [SOR]: C, multiple randomized controlled trials [RCTs] supporting disease-oriented evidence). Significant variations in BP are defined differently among studies (TABLE1-7). In addition, we do not have data on chronic use of oral decongestants; the longest time on medication in these trials was 4 weeks.
    URI
    https://hdl.handle.net/10355/60990
    Part of
    Journal of family practice, 66, no. 06 (2017): E1-E2
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2017

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