Should adult patients undergoing cardiac surgery receive preoperative statin therapy?
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Should adult patients undergoing cardiac surgery receive preoperative statin therapy? Evidence-based answer: In adult patients undergoing coronary artery bypass grafting (CABG), preoperative statin therapy reduces the incidence of postoperative atrial fibrillation (AF) by 50% and length of hospital stay by about a half day, but does not reduce short-term mortality. No benefit is seen with preoperative statin therapy for isolated valvular surgery in the absence of other indications for statin therapy (SOR: A, systematic reviews). Patients scheduled for CABG should receive at least 1 week of statin therapy; those undergoing emergency CABG should receive high-potency statin therapy (SOR: C, expert opinion).
Evidence-based practice 20, no. 6 (2017): 03