Got A-fib? Just DOAC it!
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Bottom line: In patients with newly diagnosed atrial fibrillation, all direct oral anticoagulants are just as effective for preventing ischemic stroke and systemic emboli as warfarin. Rivaroxaban is possibly more effective than warfarin (with equal bleeding rates). Apixaban and dabigatran are equally effective as warfarin and have lower bleeding rates.Review and summary of: Larsen TB, Skjoth F, Nielsen PB, Kjaedgaard JN, Lip GY. Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study. BMJ. 2016; 353:i3189.
Evidence-based practice 20, no. 6 (2017): 04