Which infants need lumbar puncture (LP) for suspected serious bacterial infection?
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Which infants need lumbar puncture (LP) for suspected serious bacterial infection? Evidence-based answer: The evidence is unclear. Comparison of the Boston, Philadelphia, Milwaukee, and Rochester protocols for serious bacterial infection (SBI) in infants showed no protocol was superior to another (SOR: A, meta-analysis of prospective and retrospective studies). C-reactive protein (CRP) is the most accurate individual laboratory value for ruling out SBI in an infant younger than 90 days (SOR: A, meta-analysis of prospective and retrospective studies). Clinical guidelines support LP in febrile infants less than 28 days old, but may not be indicated for age greater than 29 days if they meet low-risk criteria (SOR: C, opinion, clinical guideline).
Evidence-based practice 20, no. 7 (2017): 12-13