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dc.contributor.advisorSun, Jianguo, 1961-eng
dc.contributor.authorChen, Ping, 1984-eng
dc.date.issued2009eng
dc.date.submitted2009 Springeng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on Feb 11, 2010).eng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionDissertation advisor: Dr. (Tony) Jianguo Suneng
dc.descriptionVita.eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionPh.D. University of Missouri--Columbia 2009eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Statisticseng
dc.description.abstractFailure time data arise in many fields and can involve different types of censoring structures and missing information. We consider three cases: right-censored data with missing censoring indicators, clustered current status data, and clustered interval-censored data. Chapter 2 discusses regression analysis of right-censored failure time data with missing censoring indicators and presents an efficient estimation procedure based on the EM algorithm. The simulation study performed indicates that the proposed methodology performs well for practical situations. An illustrative example from a breast cancer clinical trial is provided. Chapter 3 discusses regression analysis of clustered current status data. For inference, a Cox frailty model and a two-step EM algorithm are presented. A simulation study was conducted for the evaluation of the proposed methodology and indicates that the approach performs well for practical situations. An illustrative example from a tumorigenicity experiment is provided. Chapter 4 generalizes the study of Chapter 3 to clustered interval-censored data. Chapter 5 discusses some directions for future research.eng
dc.format.extentvii, 72 pageseng
dc.identifier.oclc514118371eng
dc.identifier.urihttp://hdl.handle.net/10355/6144eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartof2009 Freely available dissertations (MU)eng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. Graduate School. Theses and Dissertations. Dissertations. 2009 Dissertationseng
dc.subject.lcshStatisticseng
dc.subject.lcshFailure time data analysiseng
dc.subject.lcshRegression analysiseng
dc.titleStatistical analysis of failure time data with missing informationeng
dc.typeThesiseng
thesis.degree.disciplineStatistics (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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