dc.contributor.advisor | Glaser, Rainer, 1957- | eng |
dc.contributor.author | Liu, Yang, 1974 Dec. 2- | eng |
dc.date.issued | 2008 | eng |
dc.date.submitted | 2008 Fall | eng |
dc.description | Title from PDF of title page (University of Missouri--Columbia, viewed on Feb. 18, 2010). | eng |
dc.description | The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. | eng |
dc.description | Dr. Rainer Glaser, Thesis Supervisor. | eng |
dc.description | M.S. University of Missouri--Columbia 2008. | eng |
dc.description.abstract | 5(4)-aminoimidazole-4(5)-carboxamide (AICA and TAICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular. Biotic nucleobase synthesis has been studied in great detail and its chemistry and biochemistry are understood very well. In contrast, hypotheses regarding prebiotic nucleobase syntheses remain controversial. While such studies focused on aqueous solution chemistry for half a century, planetary nucleobase syntheses in frozen solids (ice) and other extreme environments have been explored in the past two decades. Spectacular advances in observational astronomy and the evolving knowledge about the chemistry and physics of the interstellar medium (ISM) suggest new options and the very possibility of prebiotic nucleobase synthesis in the cold ISM. The discourse about prebiotic chemistry in interstellar space relies on observational astronomy. Hence, precise knowledge is required about the spectroscopic properties of presumed intermediates together with knowledge of their structural preferences and their isomerization dynamics. Here, we report on the structure and dynamics of AICA in a variety of solvents and the gas phase. The interplay between CC- and CN- rotations are discussed as well. | eng |
dc.description.bibref | Includes bibliographical references | eng |
dc.format.extent | vii, 63 pages | eng |
dc.identifier.oclc | 535480275 | eng |
dc.identifier.uri | https://hdl.handle.net/10355/6281 | |
dc.identifier.uri | https://doi.org/10.32469/10355/6281 | eng |
dc.language | English | eng |
dc.publisher | University of Missouri--Columbia | eng |
dc.relation.ispartofcommunity | University of Missouri-Columbia. Graduate School. Theses and Dissertations. Theses. 2008 Theses | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | |
dc.subject | Prebiotic nucleobase synthesis. | eng |
dc.subject | Prebiotic nucleobase synthesis | eng |
dc.subject.lcsh | Purines -- Synthesis | eng |
dc.subject.lcsh | Cosmochemistry | eng |
dc.title | Variable-temperature [superscript 1]H-NMR and AB initio study of 5-amino-imidazole-4-carboxamide (AICA) : competing paths for amide-H scrambling | eng |
dc.type | Thesis | eng |
thesis.degree.discipline | Chemistry (MU) | eng |
thesis.degree.grantor | University of Missouri--Columbia | eng |
thesis.degree.level | Masters | eng |
thesis.degree.name | M.S. | eng |