Browsing 2018 UMKC Dissertations - Freely Available Online by Thesis Semester "2018 Fall"
Now showing items 1-20 of 24
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Age and Gender Effects on Strain Response and Biomechanical Performance of C57BL/6 Mice
(University of Missouri -- Kansas City, 2018)Osteoporosis is a systemic skeletal disease resulting in low bone mass and micro architectural deterioration of bone tissue. It causes a consequent increase in bone fragility and susceptibility to fracture. This age-related ... -
An Approach for Fast Score Computation in Bayesian Network Structure Learning Over Large-Scale Distributed Data
(University of Missouri -- Kansas City, 2018)On a fundamental level, Bayes’ theorem enables us to utilize prior knowledge to determine the probability of an event. In consequence, its suitability for probabilistic reasoning has lead to its employment in probabilistic ... -
Black Caribbeans’ Post Migration Wellbeing-Are Religiosity and Social Support Enough to Protect Against Acculturative Stress?
(University of Missouri -- Kansas City, 2018)The relationship between well-being, religion, and/or social support has previously been observed in the African American community, both as a main effect and as moderator of predictors of well-being. Religion and ... -
A Case Study of the Literacy Experiences of 3rd Grade Struggling Readers with the Use of Interactive Digital Books
(University of Missouri -- Kansas City, 2018)Students who score one or more grade levels below the standard expectations in reading tests are defined as struggling readers. Struggling readers have difficulty in reading and/or comprehending a text, which affects ... -
Clear, Aqueous Topical Nanomicelle Formulation For Diabetic Macula Edema
(University of Missouri -- Kansas City, 2018)The objective of this study was to develop a clear aqueous mixed nanomicellar formulation (NMF) of hydrophobic drugs for diabetic macula edema. The hydrophobic drugs include triamcinolone acetonide (TA), fluocinolonce ... -
Cost Optimization and Load Balancing of Intra and Inter Data Center Networks to Facilitate Cloud Services
(University of Missouri -- Kansas City, 2018)For cloud enterprise customers that require services on demand, data centers (DC) must allocate and partition data center resources in a dynamic fashion. We consider the problem of allocating data center resources for ... -
Deciphering of packing signal hypothesis in bacterophage RNA recognition by the MS2 capsid protein in virus assembly
(University of Missouri -- Kansas City, 2018)MS2 is a classical example of a single-stranded RNA virus for which the genomic RNA plays pivotal roles in the virus assembly process. Multiple dispersed RNA se quence/structure motifs, packaging signals (PSs) varying ... -
Development of Protein Based PCBP2 siRNA Nanocomplex for Liver Fibrosis Therapy
(University of Missouri -- Kansas City, 2018)The objective of this dissertation is to develop a protein-based siRNA nanocomplex for the treatment of alcoholic liver fibrosis. Our laboratory recently discovered that silencing the poly (rC) binding protein 2 (PCBP2) ... -
Development of Targeted siRNA Therapeutics for Triple Negative Breast Cancer and Liver Fibrosis
(University of Missouri -- Kansas City, 2018)The objective of this dissertation is to develop various systems to deliver small interfering RNA (siRNA) for the treatment of triple negative breast cancer (TNBC) and liver fibrosis. siRNAs targeting vascular endothelial ... -
Enhancing Development in the Saudi Renewable Energy Sector: A Promising Strategy for Job Creation and Economic Diversification
(University of Missouri -- Kansas City, 2018)Unemployment, a critical modern problem, has economic as well as social costs. While its economic cost can be illustrated through the loss of the value of labor, its social costs include divorce, addiction to illegal ... -
Essays on Investment Stagnation and Financialization
(University of Missouri -- Kansas City, 2018)The three essays composing this manuscript examine the problem of capital accumulation from three distinct perspectives. the first essay offers a historical-dynamical view into the work of the pioneer of investment stagnation, ... -
Feasibility and Acceptability of a SystemCHANGE™ Intervention to Improve Medication Adherence in Older Adult Stroke Survivors: A Pilot Randomized Controlled Trial
(University of Missouri -- Kansas City, 2018)Purpose: The purpose of this study is to evaluate the feasibility, intervention mechanism, and potential effectiveness of the SystemCHANGE™ (Change Habits by Applying New Goals and Experiences) intervention in older ... -
Instruction Type and Student Major as they Relate to Student Success in College Level Developmental Mathematics Classes
(University of Missouri -- Kansas City, 2018)The low success rate of developmental (or remedial) mathematics courses is a hot topic at the higher education level. In this research, student success is considered in terms of final grade, D/F percentage, and withdrawal ... -
Latinx Women’s Disordered Eating: Considering Culturally Relevant Variables in the Objectification Theory Framework
(University of Missouri -- Kansas City, 2018)Using an objectification theory lens, the purpose of this study was to better understand religious/spiritual coping and acculturative stress as moderators in the relationship among sexual objectification, internalization ... -
Novel Prodrugs and Self-Assembling Nanocarriers to Improve Drug Delivery
(University of Missouri -- Kansas City, 2018)PART I: DIPEPTIDE PRODRUG APPROACH TO IMPROVE INTESTINAL ABSORPTION OF LOPINAVIR Lopinavir (LPV), a highly potent second-generation HIV-1 protease inhibitor, is currently indicated in HIV-1 infection. However, poor ... -
A Paradoxical Reality: The Blessings and Burdens of the African American Female Educational Leader
(University of Missouri -- Kansas City, 2018)The African-American female educational leadership experience is an interesting and unique journey toward personal and professional achievement. This journey proves to be quite precarious in that it is not unusual for ... -
Performance-Based Fundraiser Compensation: An Analysis of Preference, Prevalence and Effect
(University of Missouri -- Kansas City, 2018)This dissertation examines the preference for and prevalence of performance-based compensation and the relationship between it and productivity within the sample population of professional fundraisers. It reviews the ... -
Preparation of Pentablock Nanomicellar Formulations for Prostate Cancer Drug Delivery Systems
(University of Missouri -- Kansas City, 2018)This study is divided into three specific aims. Specific aim #1 focused on synthesis of pentablock co-polymer using monomers of L-lactide, ε-caprolactone and ethylene-glycol with varied molecular weights, (ii) ... -
The Relations Among Outness, Authenticity, and Well Being for Bisexual Adults
(University of Missouri -- Kansas City, 2018)Outness, a proximal minority stressor for sexual minority people, demonstrated inconsistent relationships with well-being. A possible explanation for these varied findings is that characteristics of one’s sexual minority ... -
Role of Redox-Active Trace Metal (RATM) Oxidants in the Regulation of Toll-Like Receptor 4 (TLR4) Signaling-Mediated Inflammatory Phenotype in Synovial Fibroblasts
(University of Missouri -- Kansas City, 2018)While the involvement of oxidant stress in rheumatoid arthritis (RA) has been suspected, the role of redox-active trace metals (RATM) as exogenous pro-oxidants in the pathogenesis of RA has not yet been investigated. ...