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dc.contributor.authorLu, Yunkaieng
dc.contributor.authorThiagarajan, Ganesh, 1963-eng
dc.contributor.authorJohnson, Mark L. (Mark Louis)eng
dc.contributor.corporatenameUniversity of Missouri (System)eng
dc.contributor.meetingnameMissouri Life Sciences Summit (2010: University of Missouri--Kansas City)eng
dc.date.issued2010-03eng
dc.descriptionComputational Infrastructure and Informatics Poster Sessioneng
dc.description.abstractIt has been hypothesized that osteocytes are stimulated by local strain distribution within the bone subjected to mechanical loadings. This collaborative research project between bone biologists and mechanical engineers is attempting to identify local strain fields around osteocytes that can account for their behavior in response to loading. Using CT images we have built and conducted an extensive finite element study of the mouse forearm. Our model incorporates many components of forearm anatomy not previously included in these models such as the radius and marrow cavities. The results of the current research will shed light on how bone perceives mechanical load and the pathway whereby a physical load is transduced into a biochemical signal that eventually results in new bone formation. The study will help in developing new treatments for bone diseases such as osteoporosis.eng
dc.identifier.urihttp://hdl.handle.net/10355/6323eng
dc.languageEnglisheng
dc.relation.ispartofAbstracts (Missouri Regional Life Sciences Summit 2010)eng
dc.relation.ispartofcommunityUniversity of Missouri System. Missouri Summits. Missouri Regional Life Sciences Summit 2010eng
dc.subjectosteocyteseng
dc.subjectstrain distributioneng
dc.subjectbone formationeng
dc.subject.lcshOsteocyteseng
dc.subject.lcshBones -- Growtheng
dc.titleEffect of Radius on Load Distribution within Mouse Forearm Structure: Experimental and Numerical Analyseseng
dc.title.alternativeEffect of Radius on Load/Strain Distribution between Ulna and Radius: Experimental and Numberical Analyseseng
dc.typePostereng


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