Does niacin decrease cardiovascular morbidity and mortality in CVD patients?

Abstract

Q: Does niacin decrease cardiovascular morbidity and mortality in CVD patients? A: No. Niacin doesn't reduce cardio- vascular disease (CVD) morbidity or mortality in patients with established disease (strength of recommendation [SOR]: A, meta-analyses of randomized controlled trials [RCTs] and subsequent large RCTs). Niacin may be considered as mono-therapy for patients intolerant of statins (SOR: B, one well-done RCT).