Radioactive materials: Winning the battle against cancer [abstract]

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Radioactive materials: Winning the battle against cancer [abstract]

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/643

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dc.contributor.author Lane, Stephanie R., 1982- en
dc.date.accessioned 2009-03-13T18:17:21Z en
dc.date.available 2009-03-13T18:17:21Z en
dc.date.issued 2004 en
dc.identifier.uri http://hdl.handle.net/10355/643 en
dc.description Abstract only available en
dc.description Faculty Mentor: Dr. Silvia Jurisson, Chemistry en
dc.description.abstract Radiopharmaceuticals are drugs containing a radioactive atom that can be used for the treatment of certain cancers. The radiopharmaceuticals we are interested in consist of a radioactive source contained in a molecular cage and are directed to specific sites in the body via a targeting molecule. Rhenium (Re) is a useful radioactive source that can effectively kill surrounding cells with the energy it emits. It is important for the radioactive source to be secured in the molecular cage so that it will not irradiate unwanted parts of the body. A radiopharmaceutical that will more effectively irradiate the tumor may require fewer testaments, less overall discomfort, and will hopefully result in a lower cost for patients. The focus of this study was to design the cage that would effectively hold Re. Once Re was contained in the cage it was reacted with phosphine to increase its stability. Characterization methods were employed to insure that the structure had formed, but further characterization is needed. If determined stable, radioactive Re will be tested for stability in rat serum. en
dc.language.iso en_US en
dc.publisher University of Missouri--Columbia. Office of Undergraduate Research en
dc.relation.ispartof 2004 Undergraduate Research and Creative Achievements Forum (MU) en
dc.source.uri http://undergradresearch.missouri.edu/forums-conferences/abstracts/abstract-detail.php?abstractid=113 en
dc.subject radiopharmaceuticals en
dc.subject cancer en
dc.subject Rhenium (Re) en
dc.subject molecular cage en
dc.title Radioactive materials: Winning the battle against cancer [abstract] en
dc.type Abstract en
dc.contributor.meetingname Undergraduate Research and Creative Achievements Forum (2004 : University of Missouri--Columbia) en
dc.contributor.corporatename University of Missouri-Columbia. Office of Undergraduate Research en
dc.relation.ispartofcommunity University of Missouri-Columbia. Office of Undergraduate Research. Undergraduate Research and Creative Achievements Forum


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