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dc.contributor.advisorDavis, Georgia L.eng
dc.contributor.authorBush, Danaeng
dc.date.issued2008eng
dc.date.submitted2008 Falleng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on Feb 24, 2010).eng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionDissertation advisor: Dr. Georgia Davis.eng
dc.descriptionVita.eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionPh. D. University of Missouri--Columbia 2008.eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Agronomy.eng
dc.description.abstractAccumulation of the potent carcinogen, aflatoxin, in maize poses a significant health risk to humans and animals. Most commercially grown maize lines are susceptible to infection by the fungus that synthesizes aflatoxin, and toxin levels can accumulate to dangerously high levels under the influence of a number of environmental and cellular factors. How these factors interact to control aflatoxin levels is poorly understood. The objective of this research was to identify new sources of low aflatoxin maize germplasm and to discover underlying genetic mechanisms leading to low aflatoxin accumulation in maize. Aflatoxin levels were quantified in a large set of diverse maize lines in three locations. Both tropical and temperate sources of low aflatoxin were identified. Correlation of aflatoxin levels with agronomic traits and sequences of genes responsible for some of those traits revealed statistically significant associations with traits related to plant architecture and flowering time, carotenoid content, and haplotypes for genes affecting kernel sugars, plant height and anthocyanin synthesis. Together, the results of these studies identify new sources of low aflatoxin germplasm and suggest avenues for further investigation of factors that regulate aflatoxin accumulation.eng
dc.format.extentxiii, 118 pageseng
dc.identifier.oclc556274499eng
dc.identifier.urihttps://hdl.handle.net/10355/6633
dc.identifier.urihttps://doi.org/10.32469/10355/6633eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.subject.lcshCorn -- Disease and pest resistance -- Genetic aspectseng
dc.subject.lcshAflatoxinseng
dc.subject.lcshAspergillus flavuseng
dc.titleThe role of genetic and phenotypic diversity in maize and its effects on aflatoxin accumulation by the fungus Aspergillus flavuseng
dc.typeThesiseng
thesis.degree.disciplineAgronomy (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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