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dc.contributor.authorTang, Tess
dc.contributor.authorClifton, Jospeh
dc.contributor.authorNeher, Jon
dc.contributor.authorSafranek, Sarah
dc.date.issued2018-09
dc.description2 pageseng
dc.description.abstractQ: Do statins alter the risk or progression of dementia? Evidence-based answer: No. Moderate-intensity statin therapy (with pravastatin or simvastatin) doesn’t prevent progression to dementia in patients at increased risk. No prevention studies address high-intensity statin therapy (strength of recommendation [SOR]: A, randomized controlled trials [RCTs]). Neither moderate- nor high-intensity statin therapy (with simvastatin or atorvastatin, respectively) improves existing mild to moderately severe Alzheimer’s or vascular dementia (SOR: A, RCTs). Although statin use is associated with a mild, rare, reversible delirium, it isn’t linked to permanent cognitive decline (SOR: C, expert opinion).eng
dc.description.sponsorshipTess Lang, MD; Joseph Clifton, PharmD; Jon Neher, MD, Valley Family Medicine Residency, University of Washington at Valley Medical Center, Renton ; Sarah Safranek, MLIS, University of Washington Health Sciences Library, Seattle.eng
dc.identifier.citationJOURNAL OF FAMILY PRACTICE | SEPTEMBER 2018 | VOL 67, NO 9: 578-579.eng
dc.identifier.urihttps://hdl.handle.net/10355/66442
dc.titleDo statins alter the risk or progression of dementia?eng


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