[-] Show simple item record

dc.contributor.advisorJurisson, Silvia S. (Silvia Sabine)eng
dc.contributor.authorBallard, Beau, 1980-eng
dc.date.issued2008eng
dc.date.submitted2008 Falleng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on Feb 25, 2010).eng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionDissertation advisor: Dr. Silvia Jurisson.eng
dc.descriptionVita.eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionPh. D. University of Missouri--Columbia 2008.eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Chemistry.eng
dc.description.abstract[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] [Superscript 105]RH has attractive nuclear and chemical properties to be investigated as a nuclide for development of potential radiopharmaceuticals. Complexes of Rh(III) are kinetically inert with respect to ligand exchange. [superscript 105]RH is produced by neutron irradiation of an enriched 104Ru target at the University of Missouri Research Reactor (MURR) in high specific activity, by separation from the target material. Chelate systems comprised of tertiary phosphines may serve as internal reducing agents, thus limiting the amount of ethanol and decreasing the temperatures required for labeling [superscript 105]RH. The chelate systems PS2, P2N2, and P2S2 have been investigated for use as bifunctional chelates (BFCs). Ligands were synthesized and evaluated as potential chelates for [superscript 105]RH. Labeling was investigated using both natural Rh as well as radioactive [superscript 105]RH produced at MURR. These systems focus on differences in chelating atoms and hydrophobicity as methods for optimization of labeling conditions for [superscript 105]RH.-From public.pdfeng
dc.format.extentxi, 143 pageseng
dc.identifier.oclc565882721eng
dc.identifier.urihttps://hdl.handle.net/10355/6693
dc.identifier.urihttps://doi.org/10.32469/10355/6693eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.rightsAccess is limited to the campuses of the University of Missouri.eng
dc.subject.lcshRhodium -- Isotopeseng
dc.subject.lcshRadiopharmaceuticals -- Designeng
dc.subject.lcshChelateseng
dc.titleSynthesis and evaluation of ¹⁰⁵Rhodium (III) complexes of phosphine chelate systemseng
dc.typeThesiseng
thesis.degree.disciplineChemistry (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


Files in this item

[PDF]
[PDF]
[PDF]

This item appears in the following Collection(s)

[-] Show simple item record