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    Does left atrial appendage closure reduce stroke rates as well as oral anticoagulants and antiplatelet meds in A-fib patients?

    Careyva, Beth
    Keister, Drew
    Mathieu, Susan
    Wilson, Lynn
    Nashelsky, Joan
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    [PDF] CLINICALINQUIRIES-Jan2019.PDF (319.9Kb)
    Date
    2019
    Format
    Article
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    Abstract
    Q: Does left atrial appendage closure reduce stroke rates as well as oral anticoagulants and antiplatelet meds in A-fib patients? EVIDENCE-BASED ANSWER: Yes. Left atrial appendage closure (LAAC) with the Watchman device is noninferior to vitamin K antagonists (VKAs) and non-VKA oral anticoagulants (NOACs) for adults with nonvalvular atrial fibrillation (NVAF) and 1 additional stroke risk factor (strength of recommendation [SOR]: A, multiple meta-analyses). LAAC has consistently been shown to be superior to antiplatelet therapy (SOR: A, single meta-analysis). One randomized controlled trial (RCT) demonstrated superiority of LAAC to VKA (SOR: B, single RCT).
    URI
    https://hdl.handle.net/10355/67272
    Part of
    Journal of family practice, 68, no. 01 (2019): 51-52.
    Rights
    OpenAccess.
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
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    • Clinical Inquiries, 2019

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