Genetically-modified animals: powerful tools for biomedical research

Abstract

The University of Missouri houses three National Institutes of Health (NIH), National Center for Research Resources (NCRR) animal resource centers. These animal resource centers are: (1) the Mutant Mouse Regional Resource Center (MMRRC); (2) the Rat Resource and Research Center (RRRC); and the National Swine Resource and Research Center (NSRRC). These animal centers provide genetically modified animal models of human health and disease for comparative medicine research investigators. Critser will describe the goals and functions of these animal resource centers and illustrate how investigators can access these animal models, as well as the ancillary services the resource centers provide.