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dc.contributor.authorJackman, Roberteng
dc.contributor.authorHamilton, Andreweng
dc.date.issued2019eng
dc.description.abstractQ: Does withholding an ACE inhibitor or ARB before surgery improve outcomes? EVIDENCE-BASED ANSWER: A GUARDED YES, because the evidence of benefit is from observational studies and applies to noncardiac surgery. Withholding angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) 24 hours before noncardiac surgery has been associated with a 30-day lower risk for all-cause death, stroke, myocardial injury, and intraoperative hypotension (18% adjusted relative risk reduction). The finding is based on 1 international prospective cohort study and, of note, is an association and a likelihood of benefit. Confirmation would require a large randomized trial (RCT; strength of recommendation [SOR]: B, good-quality international prospective cohort study).eng
dc.description.sponsorshipRobert Jackman, MD Cascades East Family Medicine Residency, Oregon Health and Science University, Portland; Andrew Hamilton, MS, MLS Cascades East Family Medicine Residency, Oregon Health and Science University, Portlandeng
dc.identifier.urihttps://hdl.handle.net/10355/68141
dc.languageEnglisheng
dc.publisherFamily Physicians Inquiries Networkeng
dc.relation.ispartofcollectionClinical Inquiries, 2019 (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Networkeng
dc.relation.ispartofseriesJournal of family practice, 68, no. 04 (May 2019): 238-239eng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.titleDoes withholding an ACE inhibitor or ARB before surgery improve outcomes?eng
dc.title.alternativeDoes withholding an angiotensin-converting enzyme inhabitor or angiotensin receptor blocker before surgery improve outcomes?eng
dc.typeArticleeng


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