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    •   MOspace Home
    • University of Missouri-Columbia
    • Graduate School - MU Theses and Dissertations (MU)
    • Theses and Dissertations (MU)
    • Dissertations (MU)
    • 2018 Dissertations (MU)
    • 2018 MU dissertations - Freely available online
    • View Item
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    Impact of sutherlandia frutescens on hepatic steatosis in high-fat fed rats

    Nguyen, Nhu Y.
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    [PDF] research.pdf (1.358Mb)
    Date
    2018
    Format
    Thesis
    Metadata
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    Abstract
    Hepatic steatosis is closely associated with development of obesity and type II diabetes mellitus. Western medicine for these metabolic conditions is less accessible to many developing countries because of cost, availability and need for clinical monitoring. These impediments might be addressed by development of evidence-based phytotherapies, especially those that are currently used and for which evidence of safety and efficacy can be provided ... Overall, this study provides a better understanding of the beneficial effects of Sutherlandia on hepatic steatosis by showing that consumption of this plant extract reduced HFD-induced accumulation of hepatic triglycerides by a mechanism that may involve increased fatty acid oxidation. This medicinal plant, therefore, may be a promising phytotherapy for hepatic conditions involving excess triglyceride accumulation.
    URI
    https://hdl.handle.net/10355/69869
    Degree
    Ph. D.
    Thesis Department
    Genetic area program (MU)
    Rights
    OpenAccess
    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Copyright held by author.
    Collections
    • 2018 MU dissertations - Freely available online
    • Genetics Area Program electronic theses and dissertations (MU)

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