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Comparative oncology and clinical translation of glyco protein conjugated gold nano therapeutic agent (GA-198AuNP) [abstract]
(2010)
As part of our efforts toward clinical translation of GA-198AuNP, our studies are focused on therapeutic efficacy of nanoparticulate GA198AuNP agent in dogs with prostatic carcinoma. The overall goal is to gain clinical ...
Creation of 'Super Avastin': A New Nanomedicine Approach for the Treatment of PXE and AMD [abstract]
(2010-02)
Nanomedicine is an emerging medical area that utilizes nanoparticles for the detection and treatment of diseases. The ubiquitous place of gold in Nanomedicine stems from its chemical ability to serve in an unoxidized state ...
Clinical Translation of Nanopharmaceuticals for Cancer Therapy [abstract]
(2010-02)
The most recent study involving 77,000 North American men has shown that regular prostate specific antigen (PSA) screening did not provide accurate diagnosis of prostate cancer and therefore did not save lives of cancer ...
Early Breast Cancer Detection Using Fluorescence Mediated Tomographic Imaging [abstract]
(2010)
Development of reliable technologies for early detection and screening of breast cancer is significant since the overall accuracy of traditional mammography remains low for diagnosis of benign and malignant lesions. In ...
A Comparative Study between Antibody and Peptide Conjugated Gold Nanoparticles for In Vivo Targeting of EGFR in Pancreatic Cancer Bearing Mice Models [abstract]
(2010-03)
Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States due to its severe aggressiveness and lethal malignancy. Epidermal Growth Factor Receptor (EGFR) is over expressed in more than 95% ...
Development of Absorption and Fluorescence Probes Based on Mouse Model for Molecular Optical Imaging [abstract]
(2010)
In this work we summarize our collaborative research on a project to develop absorption and fluorescence targeting probes. Several groups from University of Missouri and Harry S. Truman Memorial Veteran's Hospital including ...
A Novel Method to Monitor Sequential Displacement of Capped Ligands in Gold Nanoparticles [abstract]
(2010-02)
Nanochemistry of ligand displacement reactions has attracted much attention in recent years for the development of myriad of new gold nanomaterials. Gold nanoparticles have shown applications ranging from tumor imaging ...