Shared more. Cited more. Safe forever.
    • advanced search
    • submit works
    • about
    • help
    • contact us
    • login
    View Item 
    •   MOspace Home
    • University of Missouri-Columbia
    • Office of Undergraduate Research (MU)
    • Undergraduate Research and Creative Achievements Forum (MU)
    • 2004 Undergraduate Research and Creative Achievements Forum (MU)
    • View Item
    •   MOspace Home
    • University of Missouri-Columbia
    • Office of Undergraduate Research (MU)
    • Undergraduate Research and Creative Achievements Forum (MU)
    • 2004 Undergraduate Research and Creative Achievements Forum (MU)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    advanced searchsubmit worksabouthelpcontact us

    Browse

    All of MOspaceCommunities & CollectionsDate IssuedAuthor/ContributorTitleSubjectIdentifierThesis DepartmentThesis AdvisorThesis SemesterThis CollectionDate IssuedAuthor/ContributorTitleSubjectIdentifierThesis DepartmentThesis AdvisorThesis Semester

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular AuthorsStatistics by Referrer

    Anatomical organization of pathways in the locomotor command system of the lamprey [abstract]

    Wolf, Ryan
    View/Open
    [PDF] Anatomical organization of pathways.pdf (26.30Kb)
    Date
    2004
    Contributor
    University of Missouri-Columbia. Office of Undergraduate Research
    Format
    Abstract
    Metadata
    [+] Show full item record
    Abstract
    In vertebrates, locomotor behaviors are initiated by groups of neurons in the brain, called locomotor command systems, that project to neural networks in the spinal cord, called central pattern generators (CPGs). The output neural elements of the command system are reticulospinal (RS) neurons. The lamprey, a lower vertebrate, is an excellent model for studying locomotion because its swimming behavior is relatively simple and its nervous system is easier to analyze than those of more complex animals. Recent studies using larval sea lamprey (P. marinus) have hypothesized that RS neurons receive inputs from neurons in higher brain areas in the ventromedial diencephalon (VMD) and dorsolateral mesencephalon (DLM) (Paggett et al., in press). For example, VMD- or DLM-initiated locomotor activity is abolished when RS neurons activity is blocked. In addition, injection of horseradish peroxidase (HRP), an anatomical tracer, in the vicinity of RS neurons retrogradely labels a few neurons in the VMD and DLM. However, the numbers of labeled neurons in the VMD and DLM are lower than we would expect. Therefore, the above model would be significantly strengthened if better anatomical data could be obtained. In the present study, a different anatomical tracer, called biocytin, was injected into reticular nuclei in an attempt to retrogradely label larger numbers of neurons in the VMD and DLM. At present, we have shown that biocytin is an effective retrograde tracer, and we are determining if this technique can be used to support our model of the locomotor command system.
    URI
    http://hdl.handle.net/10355/714
    Part of
    2004 Undergraduate Research and Creative Achievements Forum (MU)
    Collections
    • 2004 Undergraduate Research and Creative Achievements Forum (MU)

    Send Feedback
    hosted by University of Missouri Library Systems
     

     


    Send Feedback
    hosted by University of Missouri Library Systems