Recent Submissions

  • What is the best treatment for PID in a pregnant woman? 

    Rossato, Jennifer; Rowland, Kathleen (Family Physicians Inquiries Network, 2008-12)
    The Centers for Disease Control and Prevention (CDC) recommends inpatient admission for intravenous (IV) antibiotics for pregnant women with pelvic inflammatory disease (PID) because of the risk of maternal and fetal ...
  • What is the best treatment for nausea and vomiting of pregnancy? 

    Kirchoff, Jeremy; Lyon, Corey (Family Physicians Inquiries Network, 2008-12)
    Antihistamines, thiethylperazine (a phenothiazine), pyridoxine (vitamin B6), and ginger are all effective for the relief of nausea. (SOR A, based on a meta-analysis.) The effect of these agents on vomiting is less clear. ...
  • What is the best prophylaxis for menstrual migraine? 

    Barrie, Jamie G.; Rodriguez, Jose E. (Family Physicians Inquiries Network, 2008-12)
    Oral naratriptan results in slightly fewer headache days than placebo in patients with menstrual migraines. (SOR A, based on consistent randomized controlled trials [RCTs].) Naproxen and magnesium therapy are also more ...
  • What is the relative effectiveness and safety of second-generation antidepressants? 

    Gallimore, Casey (Family Physicians Inquiries Network, 2008-12)
    While some small differences have been found between agents, selective serotonin reuptake inhibitors (SSRIs) and non-SSRI second-generation antidepressants generally have similar efficacy and discontinuation rates when ...
  • New point-of-care Chlamydia test comparable to PCR 

    Rowland, Kate (Family Physicians Inquiries Network, 2008-12)
    More than 1 million cases of genital Chlamydia trachomatis infection were diagnosed in the United States in 2006, making it the most common sexually transmitted infection. Most of these diagnoses were in young women: females ...
  • 140 years of evidence 

    Neher, Jon O. (Family Physicians Inquiries Network, 2008-12)
    This letter from the editor of Evidence Based Practice reflected upon the changes in medical advice and treatment over the past 140 years.
  • Is physician-delivered motivational interviewing effective for smoking cessation? 

    Rollins, Vanessa (Family Physicians Inquiries Network, 2008-12)
    Physician-delivered motivational interviewing appears to be more effective for smoking cessation than physician-delivered brief advice. Additional research is needed to address effective length of intervention as well as ...
  • Is eating sushi safe during pregnancy? 

    Spogen, Daniel; Passalacqua, Brian (Family Physicians Inquiries Network, 2008-12)
    There is no published research directly evaluating the use of narcotics to treat patients with chronic daily headache. The risks of narcotic use are well known. Nevertheless, narcotics may have some value in carefully ...
  • Bystolic®: a β-blocker with benefits? 

    Hachey, David M.; Higginbotham, Tanner (Family Physicians Inquiries Network, 2008-12)
    Bystolic (nebivolol) has not demonstrated superiority to other β-blockers for lowering blood pressure (BP), but may be associated with fewer side effects. It has been evaluated only in studies assessing the intermediate ...
  • Breast Implants and Cancer Screening 

    Family Physicians Inquiries Network (Family Physicians Inquiries Network, 2008-12)
    Breast implants are one of the most popular cosmetic and reconstructive plastic surgery procedures done today. They help women feel attractive and self-confident. However, many women are unaware that having implants may ...
  • Do women who have had a hysterectomy for benign reasons still need annual Papanicolaou smears? 

    Cole, Sarah; Meyer, Stephanie (Family Physicians Inquiries Network, 2008-11)
    Routine annual Papanicolaou (Pap) smears of the vaginal vault of women who have undergone hysterectomies for benign reasons are abnormal approximately only 1% of the time, with a 95% false-positive rate. (SOR B, based on ...
  • What is the workup of delayed menarche? 

    Campbell, Robert J.; Nagy, Suzanne; Collver, Rebecca (Family Physicians Inquiries Network, 2008-11)
    In all cases of delayed menarche, a comprehensive history and physical exam should be completed. Serum studies for follicle-stimulating hormone (FSH), leuteinizing hormone (LH), thyroid-stimulating hormone (TSH), and ...
  • Should you suffer the cost of acne? 

    Liday, Cara (Family Physicians Inquiries Network, 2008-11)
    Solodyn® is a new extended-release (ER) formulation of minocycline indicated for the treatment of inflammatory lesions of non-nodular, moderate to severe acne vulgaris. It is dosed once a day and was formulated to reduce ...
  • Potential links between arterial and venous clotting disorders 

    Neher, Jon O. (Family Physicians Inquiries Network, 2008-11)
    Venous thromboembolic disorders (including deep venous thrombosis [DVT] and pulmonary embolism [PE]) appear to be clinically distinct processes from thrombotic atherosclerotic diseases (leading to myocardial infarction ...
  • Miscarriage risk and caffeine use in early pregnancy 

    Preimesberger, Amanda; Lozeau, Anne-Marie (Family Physicians Inquiries Network, 2008-11)
    Low to moderate caffeine intake (<200 mg/d) has not been shown to significantly increase miscarriage risk. Evidence is mixed concerning higher doses. Several cohort studies found an association between an increased risk ...
  • Inducing Labor for Childbirth 

    Family Physicians Inquiries Network (Family Physicians Inquiries Network, 2008-11)
    Inducing labor means to start the process of childbirth, using artificial means to cause the womb to begin contractions (labor pains). Surveys have estimated that up to 44% of pregnant women in the United States choose to ...
  • How often can proton pump inhibitors (PPIs) be successfully withdrawn from patients with GERD? 

    Burrow, Kara; Stiles, Melissa M. (Family Physicians Inquiries Network, 2008-11)
    In patients with reflux esophagitis, symptoms return about 75% of the time after stopping PPIs. (SOR A, based on a systematic review.) In patients with endoscopy- negative reflux disease, symptoms return about half the ...
  • How effective is antibiotic therapy for preventing complications of streptococcal pharyngitis? 

    Reed, Karen; Kulie, Teresa (Family Physicians Inquiries Network, 2008-11)
    Antibiotic treatment for group A streptococcal (GAS) pharyngitis reduces suppurative and nonsuppurative complications. However, in developed countries, the number needed to treat is extremely high. Hence, treatment decisions ...
  • Do decongestants improve or slow progression chronic or recurrent rhinosinusitis? 

    Thomas, Stephen R. (Family Physicians Inquiries Network, 2008-11)
    While decongestants are recommended for chronic or recurrent rhinosinusitis and have relatively safe side effect profiles (SOR C, based on expert opinion), no research has been published that directly evaluates their use, ...
  • Do cold compresses and antihistamines improve healing after a brown recluse spider bite? 

    Kelley, Jennifer (Family Physicians Inquiries Network, 2008-11)
    No evidence-based studies are available that adequately address this question. Supportive care that includes local ice and antihistamines—along with rest, immobilization, and analgesics—is generally recommended. (SOR C, ...

View more