Vitamin C for the possible prevention of complex regional pain syndrome (type 1)
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Investigators and clinicians continue to debate the pathogenesis and appropriate treatment of complex regional pain syndrome type 1 (CRPS-1). In prospective studies, CRPS-1 occurs in about 10% to 20% of patients with wrist fractures. Approximately 20% of patients have a prolonged disability after developing the syndrome. With close follow-up, the mean time from the inciting injury to the onset of the syndrome is approximately 3 months.
Evidence Based Practice 11(3): 01-03.