What is the best treatment for chronic hiccups?
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Intravenous chlorpromazine terminates chronic hiccups. (SOR C, based on a case series.) Baclofen also appears to terminate hiccups and increase hiccup-free periods. (SOR C, based on a small randomized trial and a case series.) Other drug treatments have also been used for the treatment of hiccups, yet little evidence is available to indicate that any approach is superior.
Evidence-based practice 11, no. 05 (2008): 07+