Are beta-blockers effective for treatment of neuromediated (vasovagal) syncope?
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Metoprolol is no more effective than placebo in reducing neuromediated (vasovagal) syncope. (SOR B, based on a single high-quality study.) Studies of propranolol are of low quality and conflict. Atenolol has not been studied.
Evidence Based Practice 11(6): 05.