What is the best treatment for an adult whose asthma exacerbation has not completely responded to 5 days of oral corticosteroids?
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Current guidelines recommend that patients with acute asthma exacerbations be treated with systemic corticosteroids for 5 to 10 days, so continued steroid therapy is an option. However, limited evidence suggests that a 2-week course of oral steroids may be no more effective than a 1-week course (SOR C, based on a single small randomized controlled trial with a trend favoring prolonged therapy).
Evidence Based Practice 11(8): 04.