What is the best treatment for PID in a pregnant woman?
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The Centers for Disease Control and Prevention (CDC) recommends inpatient admission for intravenous (IV) antibiotics for pregnant women with pelvic inflammatory disease (PID) because of the risk of maternal and fetal morbidity. (SOR C, based on expert opinion.) However, all of the CDC's currently recommended parenteral antibiotic regimens contain at least 1 antibiotic that is pregnancy category D. Combination therapy with ceftriaxone and a macrolide (both pregnancy category B) is a reasonable alternative. (SOR C, based on expert opinion and data from nonpregnant patients.)
Evidence Based Practice 11(12): 08.