Herpes prophylaxis during pregnancy
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Antiviral prophylaxis starting at 36 weeks' gestational age reduces both viral shedding and clinical recurrence of genital herpes simplex virus (HSV) at the time of delivery. Rates of cesarean section due to signs of recurrence at time of delivery are consequently decreased. However, neonatal infection with herpes is rare, and there is no direct proof at present that the incidence is reduced by antiviral medication use.
Evidence Based Practice 12(1): 11+.