What is the most effective form of nicotine replacement therapy for smoking cessation?
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All forms of nicotine replacement therapy improve 6-month quit rates by about 60% over placebo (yielding a 2%-8% improvement in the absolute rate). In heavily dependent patients, there is added benefit to using high-dose gum, as opposed to low-dose gum (SOR A, based on a systematic review), or to combining nicotine patches with a nicotine nasal spray (SOR B, based on a randomized controlled trial).
Evidence Based Practice 12(2): 10.