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dc.contributor.authorDavenport, Biancaeng
dc.contributor.corporatenameUniversity of Missouri-Columbia. Office of Undergraduate Researcheng
dc.contributor.meetingnameUndergraduate Research and Creative Achievements Forum (2005 : University of Missouri--Columbia)eng
dc.date.issued2005eng
dc.descriptionAbstract only availableeng
dc.descriptionFaculty Mentor: Dr. Karen L. Bennett, Molecular Microbiology and Immunologyeng
dc.description.abstractRNAinterference (RNAi) has been used in attempt sterilize Ascaris with the long-term aim of developing RNAi as an anti-parasitic agent. Cultured worms that have been injected with Ascaris iff-1 and actin dsRNA have shown that Ascaris dsRNAs can knock out gene function in the "tester" worm Caenorhabidits elegans (C. elegans). Further analysis will be done on Ascaris dsRNA. Ascaris sum is a prevalent parasite nematode of swine. The Ascaris dsRNAs that sterilize C. elegans will be tested in Ascaris sum for their ability to sterilize these parasitic worms. Also, RNAs that have proved successful in sterilizing Ascaris worms will be tested in Ascaris-infected pigs to determine whether or not they work to sterilize worms in the mammalian host.eng
dc.description.sponsorshipLife Sciences Undergraduate Research Opportunity Programeng
dc.identifier.urihttp://hdl.handle.net/10355/744eng
dc.publisherUniversity of Missouri--Columbia. Office of Undergraduate Researcheng
dc.relation.ispartof2005 Undergraduate Research and Creative Achievements Forum (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. Office of Undergraduate Research. Undergraduate Research and Creative Achievements Forumeng
dc.source.urihttp://undergradresearch.missouri.edu/forums-conferences/abstracts/abstract-detail.php?abstractid=343eng
dc.subjectanti-parasitic agenteng
dc.subjectnematodeeng
dc.subjectAscaris wormseng
dc.subjectCaenorhabidits elegans (C. elegans)eng
dc.titleCross-species RNA interference: Selected Ascaris dsRNAs can sterilize Caenorhabditis [abstract]eng
dc.typeAbstracteng


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