What is the optimal treatment duration for depression?
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Continuing the medical therapy for depression for 1 to 2 years after acute therapy reduces the rates of relapse (return of symptoms during remission) and recurrence (new episode after recovery). (SOR A, based on 2 meta-analyses with similar findings.) The length of treatment should be based on the number of episodes as well as the presence of complicating factors. (SOR C, based on expert opinion.)
Evidence Based Practice 12(4): 08.