What is the role of antioxidants in age-related macular degeneration?
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Antioxidants are no more effective than placebo in the prevention of age-related macular degeneration (SOR A, based on meta-analyses). Antioxidants (beta carotene, vitamins C and E) in combination with zinc have a modest benefit in reducing the progression to advanced macular degeneration (SOR B, based on a single randomized controlled trial).
Evidence Based Practice 12(6): 05-06.