What common problems affect the accuracy of long-term glucose monitoring?
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Red blood cell (RBC) survival varies enough in diabetic patients to affect the glycosylated hemoglobin (HbA1c). Accuracy of home glucose monitoring can also vary dramatically, depending on the machine and technique used. The clinical value of monitoring glycated serum protein (fructosamine)—which reflects the mean glucose concentration over the prior month—rather than HbA1c is unknown. (SOR C, based on bench research and exploratory cohort studies of disease-oriented evidence.)
Evidence Based Practice 12(8): 11.