Browsing Theses (UMKC) by Thesis Department "Bioinformatics (UMKC)"
Now showing items 21-40 of 49
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Extinction of Chromosomes due to Specialization is a Universal Occurrence
(2019)The human X and Y chromosomes evolved from a pair of autosomes approximately 180 million years ago. Despite their shared evolutionary origin, extensive genetic decay has resulted in the human Y chromosome losing 97% of its ... -
A genetic linkage map of the fungus phycomyces blakesleeanus for gene identification by map-based cloning
(University of Missouri--Kansas City, 2012)The Mucoromycotina is one of the basal lineages in the fungi, all of which are poorly understood. Mucormycosis is a life threatening infection caused by fungi of the order Mucorales, the most common species of which is ... -
Guideline-Directed Statin Therapy in Patients with New or Worsening Symptoms of Peripheral Artery Disease
(University of Missouri -- Kansas City, 2018)Objective: The ACC/AHA cholesterol guidelines recommend patients with peripheral artery disease (PAD) be treated with a moderate to high-intensity statin. The extent to which PAD patients with new or worsening ... -
Health costs of sickle cell disease patients from the Medical Expenditure Panel Survey, 1996-1997, 2002-2003, 2007-2008
(University of Missouri--Kansas City, 2012)Chronic conditions affect a person physically, mentally, emotion, socially, and financially. With the increase in technology and advancements in medicine, those with chronic conditions are living longer and spending more ... -
Health Status Implications for Comorbid Diabetes in Patients with Symptomatic Peripheral Artery Disease: Insights from the PORTRAIT Registry
(University of Missouri -- Kansas City, 2018)Patients with peripheral artery disease (PAD) and coexisting diabetes mellitus (DM) have an increased rate of PAD progression and reduced walking performance as compared with non-diabetic PAD patients. It is unknown, ... -
Identification of demographics and comorbidities associated with Vascular Hamartomas
(2016)Vascular hamartomas (VH) are tumor like growths that typically appear in infants and manifest as a blemish on the skin. The goal of this study is to substantiate clinical data on the demographic characteristics and ... -
Identification of novel coding single nucleotide polymorphisms associated with acute respiratory distress syndrome
(2014-07-28)ARDS is a lung condition characterized by impaired gas exchange with systemic release of inflammatory mediators, causing inflammation, hypoxemia and multiple organ failure. Disease susceptibility and progression are poorly ... -
Impact of Systematizing the Evaluation of Patients with Acute Heart Failure Presenting to the Emergency Department
(2020)The huge burden of acute heart failure (HF) on the emergency department (ED) warrants the need for a systemized method of management. The lack of a standardized care path for acute HF patients presenting to the ED has ... -
Incidence of adverse drug events in COVID-19 patients on anticoagulants: a pharmacovigilance study
(2021)Pharmacovigilance is a crucial component of today’s health science studies that allows researchers to detect, assess, understand, to ultimately prevent any adverse event associated with drugs. Today, with the world struggling ... -
Longer Right Colon Withdrawal Time and Retroflexion Duration Significantly Increases Adenoma Detection Rate: A Randomized Controlled Trial at Three Endoscopy Centers
(University of Missouri--Kansas City, 2018)Purpose Detection of adenomas is the foundation of colorectal cancer screening utilizing screening colonoscopies. Adenoma detection rate (ADR) is an increasingly utilized core quality measure for colonoscopies. ... -
Machine and Deep Learning Approach for Type 2 Diabetes Prediction Using the CDC’s BRFSS Dataset: A Retrospective Analysis
(2022)Type 2 diabetes mellitus (T2DM) is a complex metabolic disease which is characterized by persistent hyperglycemia caused by insulin resistance. It is the most prevalent type of diabetes mellitus (DM). T2DM presents a ... -
Management, and Health Status Outcomes Of Obese Patients With Symptomatic Peripheral Artery Disease: Insight From The Portrait Registry
(University of Missouri -- Kansas City, 2018)Obesity is present in 36.2%, 20.4 % and 29.0% of adults in the US, Netherlands and Australia respectively. Obesity is a risk factor for cardiovascular disease and related complications. The management and health status ... -
Menstruation and Contraception Patterns of Female Adolescent Transplant Patients
(University of Missouri--Kansas City, 2017)BACKGROUND New data and guidelines support the use of contraception in adolescents on immunosuppressants, however, there is no data regarding base knowledge and attitude toward contraception in this particular patient ... -
Mortality Risk Among Patients Who Present to Hospitals with Out-Of-Hospital Cardiac Arrest and ST-Elevation Myocardial Infarction
(2021)In the emergent setting of an ST-elevation myocardial infarction (STEMI) presenting with an out-of-hospital cardiac arrest (OHCA), decisions for immediate coronary angiography are made when the likelihood of survival is ... -
Outcomes of Immune Checkpoint Inhibitor-Mediated Colitis: Multicenter Cohort Study
(2022)Immune checkpoint inhibitor (ICI)-mediated colitis (IMC) is a common and serious toxicity. Multiple reports have described the clinical presentation and course of IMC based on limited data. This was a collaborative effort ... -
Outpatient Management of Heart Failure During the COVID-19 Public Health Emergency After Adoption of a Telehealth Model
(2022)The COVID-19 pandemic led to a dramatic change in the process of delivering outpatient care for patients with heart failure, including more reliance on telehealth to maintain care delivery. Excess mortality has been reported ... -
Patient and Physician Discordance in Reporting Symptoms of Angina: Insights From the Angina Prevalence and Provider Evaluation of Angina Relief (APPEAR) Study
(2016)A principal goal of treating patients with coronary artery disease (CAD) is to minimize their angina and optimize their quality of life. In order to accomplish this, physicians must accurately assess the presence and ... -
Predicting Obstructive Coronary Artery Disease in Patients Undergoing Coronary Angiography for Stable Angina
(2021)Accurately identifying the pre-test probability of obstructive coronary artery disease (CAD) in patients presenting with chest pain is key in determining the next steps in management. The Diamond-Forrester model, or an ... -
A Qualitative investigation of patients' transitional states of engagement in HIV-related medical care
(2014-03-20)This qualitative study was designed to investigate the factors related to engagement in HIV-related medical care and specifically periods that can be characterized as transitions in and out of care. Data were collected ... -
Racial and Ethnic Differences in Bystander Cardiopulmonary Resuscitation for Witnessed Out-of-Hospital Cardiac Arrest
(2022)Differences in bystander cardiopulmonary resuscitation (CPR) contribute to survival disparities for witnessed out-of-hospital cardiac arrest (OHCA). Whether bystander CPR rates differ by race/ethnicity for witnessed OHCAs ...