What is the most effective management for children with dyslipidemia?
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For children with monogenic dyslipidemia, statins (with appropriate diet) are more effective for improving the lipid profile than dietary treatment and better tolerated than bile acid resins. (SOR A, based on a systematic review of randomized controlled trials.) In children with nonmonogenic dyslipidemia, medications have not been studied. A combination of dietary, exercise, and behavioral interventions is more effective than diet or exercise alone. (SOR B, based on a single trial.)
Evidence Based Practice 12(9): 08.