What is the best treatment for chronic post-CABG pain?
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Evidence is insufficient to choose a single best agent for chronic post-CABG pain. However, amitriptyline, capsaicin cream, opioids, and NMDA antagonists are effective choices for other postsurgical pain syndromes and may be effective treatments of pain after coronary artery bypass grafting (CABG). (SOR C, extrapolated from randomized controlled trials [RCTs] involving other surgeries.) Gabapentin and lamotrigine, commonly used for neuropathic pain, are not effective for postsurgical neuralgia. (SOR C, based on expert opinion.)
Evidence Based Practice 12(11): 05.