For the initial management of dyspepsia, what strategy is best to prevent recurrent dyspepsia/gastritis?
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It appears there is little difference in efficacy at 1 year between a Helicobacter pylori “test-and-treat” strategy and empiric proton-pump inhibitor (PPI) treatment for initial management of patients with dyspepsia, even if the H pylori prevalence rate is as high as 25% to 30%. (SOR A, based on a meta-analysis and subsequent randomized controlled trial [RCT].)
Evidence Based Practice 12(12): 13.