Is there a role for CA-125 in the evaluation of abdominal pain?
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CA-125 testing is not specific enough in the primary evaluation of abdominal pain to be clinically useful, and would have unacceptably high false-positive rates. (SOR B, based on retrospective studies and reviews.) CA-125 may have a role in the evaluation of abdominal pain in postmenopausal women with a pelvic mass. (SOR C, based on expert opinion.)
Evidence Based Practice 12(12): 10-11.