Warfarin therapy not warranted for secondary prevention of CVD
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No data are available to support the addition or substitution of warfarin after failure of antiplatelet agents for secondary prevention of ischemic stroke. Further, warfarin may be no better than placebo at reducing the risk of noncardioembolic stroke. (Strength of recommendation [SOR] B, based on heterogeneous meta-analyses.)
Evidence Based Practice 12(12): 01-02.