2020 Dissertations (MU)
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Virus interactions with the sphingolipid network : sphingosine kinase 2 in immunosuppression, immunopathology, and viral propagation
(University of Missouri--Columbia, 2020)Sphingosine 1-phosphate (S1P) is a bioactive lipid molecule known to regulate diverse cellular functions. S1P is metabolized by the sphingosine kinases (SphK) and S1P lyase (SPL). However, little is known about the role ... -
Development of tissue based biomaterials for articular cartilage injuries
(University of Missouri--Columbia, 2020)Multiple biomaterials have been developed in this work. Decellularized porcine diaphragm extracellular matrix was homogenized and supplemented with various biomodulatory agents. It was developed as an injectable material ... -
Uncovering the genetic architecture and metabolic basis of amino acid composition in maize kernels using multi-omics integration
(University of Missouri--Columbia, 2020)Seeds are a major source of protein in human and livestock diets. Cereal grains are some of the most consumed seeds by both humans and livestock worldwide, with maize, wheat, and rice alone accounting for ~70% of the total ... -
Evaluation of use of dry-process rubber modification in asphalt mixtures
(University of Missouri--Columbia, 2020)This study explores four different facets of using dry-process rubber modification in asphalt mixtures. The first investigation was motivated by the need to understand the cracking mechanism prevalent in the dry-process ... -
Systematic review and meta-analysis of primary care-based physical activity interventions among older adults
(University of Missouri--Columbia, 2020)Background. Most healthcare providers agree that increasing physical activity (PA) in older adults is beneficial but providing effective interventions can be difficult. The purpose of this research is to determine the ... -
Linear and multilinear spherical maximal functions
(University of Missouri--Columbia, 2020)In dimensions n [greater than or equal to] 2 we obtain Lp1(Rn) x ... x Lpm(Rn) to Lp(Rn) boundedness for the multilinear spherical maximal function in the largest possible open set of indices and we provide counterexamples ... -
Application of electronic structure calculations to vibrational spectroscopy and gas encapsulation in zeolites
(University of Missouri--Columbia, 2020)Zeolites are an important class of aluminosilicate materials that have wide applications in heterogeneous catalysis, gas separations, and ion-exchange processes at industrial scales. The desire to continue doing research ... -
Disentangling alcohol-specific alcohol use disorder criteria from externalizing psychopathology using an empirically driven approach
(University of Missouri--Columbia, 2020)Within current mental disorder classification systems, alcohol use disorder (AUD) and psychopathology, more broadly, are conceptualized as distinct categorical disorders. Recent classification research has focused on ... -
Fast and robust deep neural networks design
(University of Missouri--Columbia, 2020)In the past few years, we have witnessed a rapid development of deep neural networks in computer vision, from basic image classiffcation tasks to some more advanced applications e.g. object detection and semantic segmentation. ... -
Knowledge discovery with recommenders for big data management in science and engineering communities
(University of Missouri--Columbia, 2020)Recent science and engineering research tasks are increasingly becoming dataintensive and use workflows to automate integration and analysis of voluminous data to test hypotheses. Particularly, bold scientific advances in ... -
Using (microchannel) electrochemical impedance spectroscopy to detect bacterial activities
(University of Missouri--Columbia, 2020)Even though rapid detection of molecular methods has been used in bacterial detection, (automated) liquid culture methods are still the "Gold Standard" for the detection of living bacteria, especially in cases where there ... -
User experience and robustness in social virtual reality applications
(University of Missouri--Columbia, 2020)Cloud-based applications that rely on emerging technologies such as social virtual reality are increasingly being deployed at high-scale in e.g., remote-learning, public safety, and healthcare. These applications increasingly ... -
Human behavior understanding and intention prediction
(University of Missouri--Columbia, 2020)Human motion, behaviors, and intention are governed by human perception, reasoning, common-sense rules, social conventions, and interactions with others and the surrounding environment. Humans can effectively predict ... -
Anisotropic shock response of 1,3,5-triamino-2,4,6-trinitrobenzene (TATB)
(University of Missouri--Columbia, 2020)The thermo-mechanical response of shock-induced pore collapse has been studied using non-reactive all-atom molecular dynamics (MD) and Eulerian continuum simulations for the molecular crystal 1,3,5-triamino-2,4,6-trinitrobenzene ... -
Optimization of bitterness in chocolate through roasting with analysis of related changes in important bitter compounds
(University of Missouri--Columbia, 2020)Chocolate is made from the fermented, dried, and roasted seeds of the Theobroma cacao tree, an important agricultural food crop which contains bioactive flavonoid polyphenols with beneficial health effects. Such effects ... -
Parent attachment and prosocial behaviors in Asian Indian young adults : prosocial moral reasoning and respect for family as intervening mechanisms
(University of Missouri--Columbia, 2020)The primary goal of this study was to examine the intervening roles of prosocial moral reasoning and respect for family in associations between parent attachment and prosocial behaviors in Asian Indian young adults. ... -
Development of translational models for intervertebral disc degeneration using a comparative approach for canine and human patients
(University of Missouri--Columbia, 2020)Intervertebral discs (IVDs) are unique musculoskeletal tissues within functional spinal unit organs comprising the spinal column that distribute loads and allow complex movements for vertebrates. IVD degeneration has been ... -
Medical students' narratives of peer bullying in women
(University of Missouri--Columbia, 2020)This study uncovered complicated social dynamics of women students in an accelerated, combined degree program, specifically the narratives of students who experienced peer bullying. Individual and collective narratives ... -
The effectiveness of psychoeducational interventions on quality of life for family caregivers : a systematic review and meta-analysis
(University of Missouri--Columbia, 2020)Background: Caregivers (CGs) of older adults with chronic illnesses often face consequences of caregiving that negatively impact their quality of life (QoL). Objective: To examine the overall effect of psychoeducational ... -
Harmonic wavelet analysis of surface waves at complex geotechnical sites
(University of Missouri--Columbia, 2020)The use of stress wave-based geophysical methods in geotechnical engineering has continued to grow and is now a routine component of many geotechnical site investigation programs. Surface wave methods, in particular, are ...